Myristoyl Pentapeptide-4
product description
Xi'an Le-Nutra Ingredients Inc is one of the most professional manufacturers and suppliers of myristoyl pentapeptide-4 in China, featured by quality products and low price. Please rest assured to wholesale bulk myristoyl pentapeptide-4 for sale here from our factory. Customized orders are welcome.
Myristoyl Pentapeptide-4 is a chemically synthesised, fatty acid-modified small-molecule signalling peptide that has found extensive application in cosmetic formulations, functional skincare products, and hair care formulations. Its molecular structure comprises a pentapeptide active sequence covalently linked to a myristoyl fatty acid chain. This structural design effectively enhances the molecule's lipophilic properties and skin penetration compatibility, enabling more efficient signal transduction within the skin and hair follicle microenvironment.
Within the cosmetics sector, Collasyn® 514KS is typically positioned as a functional active ingredient for eyelash and hair care applications. Existing research data and industry formulation practices indicate this signalling peptide participates in intercellular information regulation processes, supporting keratin-related biosynthetic pathways. This fulfils brand formulation requirements for enhancing structural resilience and overall condition optimisation within hair care products. Consequently, this ingredient has gained widespread adoption in premium eyelash serums, eyebrow nourishing formulations, and anti-hair loss/strengthening hair care products, establishing itself as a prominent active ingredient within these categories.

Specification
|
Product name |
Myristoyl Pentapeptide-4 |
| Other Names | Myr-KTTKS,Collasyn 514KS,Pentapeptide-4 |
|
Apperance |
White powder |
|
Purity |
98% |
|
CAS No. |
1392416-25-9 |
|
Grade |
Cosmetic grade |
|
Shelf life |
24 Months |
|
Storage |
Cool Dried Storage |
|
Packaging |
Aluminum Foil Bag / Carton |
Product Characteristics
1. Exceptional Bioavailability: The incorporation of myristoyl not only enhances the stability of the raw material but also endows it with outstanding lipophilicity, enabling rapid penetration into the hair follicle matrix to directly target dermal papilla cells.
2. Non-hormonal safety: Unlike prostaglandin-based ingredients, Myr-KTTKS does not involve hormonal regulation. Long-term use does not cause eye redness, hyperpigmentation (dark circles), or iris colour changes.
3. Gene-level induction: Clinical studies demonstrate this ingredient significantly upregulates the expression of the keratin gene KRT71, increasing protein density within the hair shaft at its source.
4. Multifunctional application: Beyond hair care, its properties as a signalling peptide also excel in promoting skin collagen synthesis and enhancing periorbital firmness.
5. Formulation stability: Exhibits exceptional chemical stability within a pH range of 4.0 to 7.0, demonstrating good compatibility with most thickeners, surfactants, and emulsification systems.

Product Efficacy
1. Deeply activates hair follicles, significantly accelerating eyelash/eyebrow growth
Myristoyl Pentapeptide-4 powder prolongs the anagen phase and shortens the telogen phase by stimulating the synthesis of beneficial proteins within follicular cells. Clinical comparisons demonstrate a visually observable increase of over 25% in eyelash length and density after 2-4 weeks of using formulations containing a 10% solution.
2. Enhances keratin levels for robust, thickened hair shafts
It effectively replenishes keratin lost within the hair structure. By increasing the cross-sectional area of the hair shaft, it renders lashes appear darker and denser while reducing breakage and shedding caused by makeup removal or friction.

3. Stimulates collagen regeneration to smooth fine lines around the eyes
Myristoyl Pentapeptide-4 raw material, a potent signalling peptide, stimulates dermal fibroblasts to produce Type I collagen. While nurturing lashes, it simultaneously repairs delicate periocular skin, enhancing eyelid elasticity and reducing age-related laxity.
4. Enhances microenvironment and fortifies follicular barrier
It optimises the microenvironment surrounding hair follicles, providing antioxidant protection and alleviating follicular inflammation caused by environmental irritants. This ensures newly grown hair emerges healthier and more resilient.
Key Features and Benefits of Hydrolyzed Oat Protein
1. Premium Eyelash Growth Serum:
As the core active ingredient currently replacing prostaglandin-based compounds within global regulatory frameworks, Myristoyl Pentapeptide-4 stands as the preferred choice for developing safe, side-effect-free eyelash serums. It integrates seamlessly into water-based or gel formulations, enabling brands to create premium eye care products emphasising ‘gentle, long-lasting effects without irritating the eyes or causing dark circles’.2. Eyebrow Thickening & Nourishing Serum:
Addressing modern consumers' concerns of sparse, brittle brows caused by frequent shaping, tattooing, or stress, this ingredient can be incorporated into dedicated eyebrow serums or intensive care oils. By strengthening hair shaft structure, this ingredient not only enhances visual density but significantly improves underlying skin health around the brows, serving as a high-conversion selling point for premium grooming lines.

3. Hair Loss Prevention & Regrowth Care:
Myristoyl Pentapeptide-4's application is expanding from the eye area to scalp care. It is suitable for scalp revitalising serums, hairline roll-on treatments, and anti-hair loss sprays. Its lipophilic properties enable excellent performance within scalp delivery systems containing moderate alcohol or alcohol-based formulations. By reactivating dormant hair follicles, it provides scientifically grounded formulation support for addressing youth-onset hair loss concerns.4. Multi-functional Eye Cream with Combined Efficacy
Within the premium anti-ageing market, this ingredient empowers dual- or even triple-action eye products—simultaneously delivering eye contour firming and fine line reduction while nourishing and promoting eyelash growth. This ‘skincare + haircare’ cross-category functionality significantly elevates the price point potential of end products and enhances brand technical premiumisation, satisfying elite consumers' pursuit of highly effective, minimalist skincare.
5. Functional Makeup System Integrating Cosmetics and Skincare
Amid the burgeoning trend of makeup skinification, Myristoyl Pentapeptide-4 bulk serves as an ideal additive for cosmetic formulations such as mascara and liquid eyeliner. Its exceptional compatibility within emulsion systems ensures consumers receive sustained peptide nourishment throughout wear, elevating conventional cosmetics into restorative ‘nourishing makeup’ that builds distinctive competitive barriers for brands.
Market Applications
According to the latest industry report for 2026, the growth of this peptide is primarily driven by the following factors:
Tightening regulations on ‘Clean Beauty’: Stringent restrictions imposed by the US FDA and the EU on hormone-based eyelash growth serums have made highly safe peptide ingredients the sole globally compliant option.
Integrated Nourishment and Therapy under Holistic Wellness: Consumers no longer seek instant cosmetic effects but pursue long-term biological improvements, making “nourishing cosmetics” the market mainstream.
Booming male grooming market: Surging demand for beard and eyebrow thickening products has opened vast blue ocean opportunities for Myristoyl Pentapeptide-4 raw material.
Cost reduction in peptide synthesis technology: As large-scale production costs decrease, this ingredient is permeating from high-end luxury skincare (priced in the tens of thousands) into the mass market for refined skincare.

Frequently Asked Questions
Q1: Which is superior when compared to Myristoyl Pentapeptide-17?
A: The two are typically used in combination. Pentapeptide-17 focuses on activating hair growth signals, whilst Pentapeptide-4 excels in promoting keratin expression and structural repair. Their synergistic action achieves accelerated hair growth where the combined effect exceeds the sum of its parts.
Q2: Does this ingredient contain prostaglandin analogues? Could it cause dark circles?
A: This constitutes a core advantage of our formulation. Myristoyl Pentapeptide-4 is a bioactive peptide composed entirely of amino acids, falling outside the categories of hormones or prostaglandin-like substances. It functions through biological signalling regulation rather than pharmacological intervention, thus avoiding eye redness, itching, pigmentation (dark circles), or iris colour changes. It complies with the world's most stringent Clean Beauty standards.
Q3: Can it be combined with other peptides or plant extracts?
A: Yes. Myristoyl Pentapeptide-4 bulk is frequently employed in multi-peptide formulations and may synergise with plant extracts, amino acids, or moisturising agents to fulfil diverse brand requirements for functional architecture and product narratives.
Q4: Is this ingredient suitable for long-term, stable supply?
A: As a mature synthetic peptide ingredient, it possesses robust industrial production foundations, making it suitable for long-term project development and large-scale applications. Consistent quality control and batch uniformity represent key advantages within the B2B supply chain.
Q5: Do you provide technical documentation and formulation support?
A: We furnish comprehensive technical documentation including COAs, MSDS, specification sheets, and stability data. We also offer ingredient selection guidance and application consultation to assist brands and OEM clients in advancing product development efficiently.
Why Choose Le-Nutra
As a specialist manufacturer of Myristoyl Pentapeptide-4, Le-Nutra Ingredients possesses extensive expertise in plant extraction and peptide synthesis. We not only supply high-purity active ingredients but are also committed to creating profound commercial value through our end-to-end service model.
Our factory-direct model, operating on a ‘research centre to warehouse’ principle, eliminates intermediary mark-ups entirely. This ensures you secure premium-quality ingredients at highly competitive, source-level pricing. Our specialised application laboratory serves not only as a production hub but also as your technical support arm. We assist in optimising formulation architecture, provide comprehensive stability testing data and ingredient compatibility advice, ensuring optimal efficacy of the raw material within your finished products.
Regarding quality control, we implement stringent controlled processes and steadfastly endorse third-party authoritative testing, ensuring quality, safety, and traceability. Furthermore, with ample stock reserves and a flexible production system, we support customised packaging from 1g R&D samples to 10kg industrial bulk orders. Our exceptional responsiveness empowers your brand to seize opportunities in fiercely competitive markets.
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