Palmitoyl Tetrapeptide-10
product description
Palmitoyl Tetrapeptide-10 is a high-performance active peptide ingredient, modified with a palmitoyl group, specifically designed for cosmetic and skincare formulations. Comprising four amino acid residues (L-lysine, L-threonine, L-phenylalanine, and L-lysine), it features a palmitoyl group introduced at the N-terminus. This modification enhances lipophilicity and skin penetration within formulations, facilitating seamless incorporation into serums, emulsions, creams, and eye care products.
As a signalling peptide, it exhibits high compatibility with skin cells and structural proteins, making it a sought-after ingredient among premium skincare brands and formulators. Suitable for anti-ageing, brightening, skin texture improvement, and multifunctional formulations, it stands as a key ingredient choice for developing high-end skincare products.
Le-Nutra Ingredients maintains a specialised active peptide production team and comprehensive manufacturing system, equipped with internationally compliant production facilities and stringent cleanroom management protocols. Each batch of Palmitoyl Tetrapeptide-10 undergoes rigorous quality control to ensure high purity, stability, and batch consistency, enabling clients to effortlessly develop stable, reliable premium skincare formulations. By choosing us, you gain not only superior-quality ingredients but also expert technical support and assured supply stability – providing robust backing for your product development and market competitiveness.

Specification
|
Product name |
Palmitoyl tetrapeptide-10 |
| Other Names | crystalide peptide, Crystalide, Pal-KTFK peptide |
|
Apperance |
White powder |
|
Purity |
99% |
|
CAS No. |
887140-79-6 |
| Molecular formula | C41H72O7N6 |
| Molecular weight | 761.05 |
|
Grade |
Cosmetic grade |
|
Shelf life |
24 Months |
|
Storage |
Cool Dried Storage |
|
Packaging |
Aluminum Foil Bag / Carton |
Product Characteristics
1. Signal Peptide Properties
Crystalide Peptide functions as a signal peptide within formulations, mimicking the role of endogenous signalling molecules. By interacting with skin cell receptors, it promotes the skin's natural repair and renewal processes. This peptide structure simulates signalling stimuli within the skin barrier, thereby enhancing cellular self-renewal efficiency.2. Palmitoyl Modification for Enhanced Penetration
The inclusion of a palmitoyl moiety improves compatibility with the skin's lipid layer, enhancing distribution and penetration within oil-in-water systems (such as emulsions, serums, and cream formulations). This facilitates deeper delivery of active ingredients.
3. Interaction with Skin's Natural Proteins
It supports maintaining the homeostasis of certain skin proteins (such as α-crystallin), which play a crucial role in skin transparency, luminosity, and quality. This improves skin texture and radiance from a fundamental level.
4. Excellent formulation compatibility
Pal-KTFK peptide demonstrates good compatibility with numerous skincare ingredients, allowing formulation with humectants, antioxidants, other peptides, or active ingredients for diverse skincare applications.
5. Low irritancy and safety profile
At appropriate concentrations, this peptide typically exhibits low irritancy and does not increase skin photosensitivity, making it suitable for most skin types.
Products Efficacy
1. Radiant, translucent luminosity
Palmitoyl Tetrapeptide-10 participates in regulating the keratinisation process, enhancing overall skin texture to achieve an even, luminous complexion with a translucent glow. By promoting internal skin equilibrium, it helps diminish dullness, revealing a crystalline clarity and amplifying natural radiance.
2. Refined texture
This active peptide helps refine surface roughness, creating a more uniform and firmer texture while optimising pore appearance. It imparts a porcelain-like smoothness to both touch and sight. Long-term formulation use enhances skin smoothness and softness.

3. Strengthen the Biological Barrier
Pal-KTFK peptide promotes the synthesis of barrier-related proteins, supporting the skin's inherent protective function. It aids in bolstering the skin's adaptability to external environmental stressors, fostering healthier, more resilient skin and enhancing the overall efficacy of skincare formulations.
4. Targeted Anti-Ageing
As a quintessential signalling peptide, it synergises with the skin's natural repair mechanisms to support the restoration and reconstruction of damaged tissue, thereby delaying signs of ageing caused by age or environmental factors. Within premium skincare formulations, it serves as a crucial ingredient in anti-ageing and multi-functional care products.
Market Applications
1. Glass Skin Polishing Essence
Palmitoyl Tetrapeptide-10 cosmetic ingredient is specifically formulated for users pursuing the Korean ‘glass skin’ effect or minimalist skincare philosophies. Such essences serve as core ingredients in premium skincare lines for brightening and texture refinement, enhancing surface uniformity and translucency to establish an ideal foundation for subsequent skincare steps.2. Tone-Up Cream
Suitable for lightweight skincare products delivering natural brightening effects, reducing reliance on makeup coverage or physical illuminating pigments. This ingredient can be incorporated into daily repair and brightening creams to create a light, natural-looking evenness of complexion.
3.Premium Makeup Primer
Suitable for pre-makeup products that smooth skin texture and optimise skin feel, helping subsequent foundation adhere more seamlessly while reducing powder caking and unevenness. As an active peptide ingredient, Palmitoyl Tetrapeptide-10 can be blended with other moisturising and repairing components in primers to elevate the overall formulation value.

4. Intensive Repair Ampoules
Formulated as high-concentration repair serums or ampoules to address dullness and roughness caused by late nights or environmental stress. Rapidly improves surface skin condition, suitable as a functional standalone product within premium skincare lines.5. Scalp/Body Polishing Lotion
For refining skin texture on specific body areas (e.g., elbows, knees, shoulders), suitable for developing premium body care lines. Incorporated into lotions or body creams, it delivers a refined, silky application experience.
6. Eye Care Products
Crystalide may be used in eye contour formulations such as eye serums and creams, ideal for creating high-end firming and anti-wrinkle skincare ranges.
7. Medical Aesthetic Post-Treatment Care and High-Performance Skincare
This active peptide ingredient is also suitable for medical aesthetic post-treatment care and high-performance skincare products. It supports the skin's self-recovery within formulations and helps enhance the overall efficacy of the product.
Market Trends
• The Rise of Bio-Polishing: Consumers are increasingly turning away from aggressive chemical peels, seeking gentler biological alternatives such as peptides.
• Minimalism and Transparency: The ‘Clean Girl Aesthetic’ trend continues to gain momentum, driving substantial market demand for ingredients that deliver a ‘no-makeup makeup’ translucent finish.
• Barrier-Repairing Brightening: Traditional whitening often compromises the skin barrier. Crystalide Peptide brightens while fortifying the barrier, aligning with contemporary ‘healthy anti-ageing’ aesthetic principles.

FAQ
Q1: Does Palmitoyl Tetrapeptide-10 cause skin thinning or sensitivity?
A: No. Unlike the forced exfoliation mechanism of AHAs/BHAs, it regulates cellular maturation and shedding through biological signalling. It actually helps strengthen the epidermal barrier, making it highly suitable for sensitive skin.
Q2: Can it be used alongside retinol?
A: Absolutely. Palmitoyl Tetrapeptide-10's soothing and barrier-strengthening properties mitigate the dryness and irritation often associated with retinol, while synergistically improving skin texture.
Q3: Why is this peptide termed the ‘crystal peptide’?
A: Because its design blueprint is derived from crystallin proteins, which maintain the transparency of the eye's lens. This peptide mimics that function in skin, reducing intracellular oxidative waste accumulation to preserve cellular clarity.
Q4: Do your ingredients support third-party testing?
A: Yes, we support purity, heavy metal, and microbial testing by any internationally recognised third-party laboratory to ensure compliance with your brand standards.
Q5: What is your minimum order quantity (MOQ)?
This can be flexibly adjusted based on packaging specifications and client requirements. Please contact us for detailed proposals.
Q6: Do you offer custom packaging?
Yes. We support various bespoke solutions ranging from small-scale samples to commercial bulk packaging.
Why Choose Le-Nutra's Palmitoyl Tetrapeptide-10
As a leading manufacturer with years of expertise in plant extraction and peptide synthesis, Le-Nutra Ingredients not only supplies high-purity Palmitoyl Tetrapeptide-10 active ingredients but is also committed to creating profound commercial value through our end-to-end service. Leveraging our factory-direct model of ‘Research Centre Direct to Warehouse’, we eliminate intermediary mark-ups entirely, ensuring you access premium-quality ingredients at highly competitive source pricing. Our specialised application laboratories serve not only as production hubs but as your technical support arm, assisting in optimising formulation architecture, providing comprehensive stability testing data and ingredient compatibility advice to ensure optimal efficacy of the active ingredient within your finished products.
Our Package











